Amended prothrombin time as a diagnostic perceptive in HIV infected patients
Sireesha K, Anuradha A, Jedhidiah ESN, Bagalad BS, Puneeth HK
Background: HIV infection is a serious disorder of the immune system and is associated with a wide range of haematological abnormalities including coagulation defects. Basic coagulation parameters like prothrombin time, partial thromboplastin time and thrombin time gets altered in HIV infected patients. Objective: The objective of the study is to analyze prothrombin time among HIV infected patients. Methods: Study group consisted of 15 HIV infected patients and control group consisted of 15 healthy volunteers. Blood sample of 2ml was collected into sodium citrate anticoagulant containers from both the groups by venepuncture. The blood samples were processed and evaluated for prothrombin time. The results were tabulated and analyzed using unpaired t-test. Results: Results showed a significant increase in prothrombin time values in the study group when compared to the control group. Conclusion: Since the basic coagulation test like prothrombin time is prolonged in HIV infected patients, it can be used as a prospective screening test to measure the quality of coagulation and to assess the possibility of complications in HIV infected patients.
Sireesha K, Anuradha A, Jedhidiah ESN, Bagalad BS, Puneeth HK. Amended prothrombin time as a diagnostic perceptive in HIV infected patients. International Journal of Academic Research and Development, Volume 5, Issue 3, 2020, Pages 113-115