International Journal of Academic Research and Development

International Journal of Academic Research and Development


International Journal of Academic Research and Development
International Journal of Academic Research and Development
Vol. 3, Issue 6 (2018)

Comparative study of active constituents of some medicinal plants along altitudinal gradient


Shreehari Bhattarai, Minu Gautam, Rajesh Tamang

Plant-based medicine for curing diseases is as old as human civilization. Medicinal plants consist of an active constituents, which are used for treating various diseases and healing of wound in humans. This paper aims to identify bioactive phytochemical constituents of selected four medicinal plants viz. Acorus calamus L. (Bojho), Eucalyptus camaldulensis Dehnh. (Masala), Artemisia indica Willd. (Titepati) and Cymbopogan winterianus Jowitt ex Bor (Citronella) and compare their concentration along altitudinal gradient in Makawanpur district, central Nepal. The plant species were selected from different altitudinal regions and the phytochemical screening was done using Gas Chromatography-Mass Spectrometry (GC-MS) to identify major active constituents. The major active constituents in Acorus calamus L. of three altitudes were β-Asarone, Isoeugenol and α-Asarone and the β-Asarone was found to be present in highest concentration from temperate region. The major active constituents in Eucalyptus camaldulensis Dehnh. of tropical and temperate region were Eucalyptol, α-Pinene, β-Pinene, D-Limonene, α-Terpineol and Viridiflorol. In sub-tropical region, Viridiflorol was absent and among the major bioactive constituents, Eucalyptol was found in highest concentration in temperate region. The major active constituents in Artemisia indica Willd. of tropical and temperate region were 7-Oxabicyclol [2.2.1] heptane, 1-methyl-4-(1-methlethyl), β-Thujone, Sabinene, Borneol and Camphor. In Artemisia indica Willd. of sub-tropical region, β-Thujone was absent and the concentration of major active constituents, 7-Oxabicyclol [2.2.1] heptane, 1-methyl-4-(1-methlethyl), was found to be highest in sub-tropical region. The major active constituents in Cymbopogan winterianus Jowitt ex Bor of tropical and sub-tropical region were Geranial, Neral, (R) - Lavandulyl acetate, D-Limonene and β-Asarone and the concentration the major active constituents (R)- Lavandulyl was found to be highest in Cymbopogan winterianus Jowitt ex Bor from sub-tropical region. The findings of this study provide the empirical support for the cultivation of Acorus calamus L. and Eucalyptus camaldulensis Dehnh. mainly in temperate region, Artemisia indica Willd. in subtropical region whereas Cymbopogan winterianus Jowitt ex Bor in tropical region so as to obtain optimum yield of major active chemical constituents.
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How to cite this article:
Shreehari Bhattarai, Minu Gautam, Rajesh Tamang. Comparative study of active constituents of some medicinal plants along altitudinal gradient. International Journal of Academic Research and Development, Volume 3, Issue 6, 2018, Pages 257-264
International Journal of Academic Research and Development International Journal of Academic Research and Development