Corona virus is causes respiratory infection which includes pneumonia, cold, sneezing and coughing and body temperature variation, digestion imbalance (diarrhea) and respiratory infection in humans. Corona virus transmitted human to human or human to animal via airborne droplets. Corona virus enters and affected in animals, some researchers have identified some specific types of cell in a nose that are the primary infection, and from mouth, sexually transmit contact through membrane and angiotensin converting enzyme-2(ACE)-2 exopeptidase receptor. WHO and European center for disease prevention and control (ECDC) advised to avoid public place and close contact to infected persons and pet animals. Initially, Corona virus (2019-nCoV) was isolated from Wuhan market China on 7th Jan 2020. While the majority of cases result in mild symptoms, some progress to pneumonia and multiorgan failure. The death per number of diagnosed cases is estimated at between 1% and 5%, but varies by age and other health conditions. The infection is spread from one person to others via respiratory droplets, often produced during coughing and sneezing. It takes 2–14 days to develop symptoms from the day of exposure. Reverse transcription‑polymerase chain reaction (RT-PCR) from a nasopharyngeal swab or oropharyngeal swab is the standard method of diagnosis. The infection can also be diagnosed from a combination of symptoms, risk factors, and a chest computed tomography scan showing features of pneumonia. Measures recommended to prevent the disease include frequent hand washing, maintaining distance from other people, and not touching one’s face. The use of masks is recommended for those who are suspected to have the virus and to their caregivers, but not the general public. As of still, there is no vaccine or specific antiviral treatment for COVID‑19; management involves treatment of symptoms, supportive care, and experimental measures. The World Health Organization declared the 2019–2020 CoV outbreak a pandemic and a Public Health Emergency of International Concern.