Studies on the antimicrobial effect of various plant extracts against Human pathogens and search for the New Drugs
Author(s): Kumaran T, Citarasu T
Abstract: Medicinal plants are considered as an important source of potentially useful structures for the development of new chemotherapeutic agents. In the present study, three selected Indian medicinal plants such as Hybanthus enneaspermus, Asparagus racemosus and Curcuma longa were analyzed for phytochemical constituents and tested for antibacterial activity against pathogens. In most of the samples all the phytochemicals i.e. reducing sugar, Terpenoids, Flavonoids, Saponins, alkaloids, cardiac glycosides, carbohydrates and phytosterols were present. Methanol and aqueous extracts of the samples of all plants were evaluated for in vitro antibacterial activity against Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa by agar plate well diffusion method. All the plant extracts showed significant antibacterial activity against the tested organisms. However, methanol extracts showed maximum inhibitory effect from this Hybanthus enneaspermus and Asparagus racemosus were showed maximum bacterial inhibition than other plants.